New York.
Scientists have developed brain cells from Human
Pee, which can be useful to treat parkinson & alzheimer.
As a person urinates, skin cells are
routinely shed from the lining in the kidney, and it’s these cells that the
researchers reprogrammed into stem cells, which can turn into any type of cell
in the body, including brain cells.
The Chinese researchers used a newer,
safer approach by harvesting skin cells that line the kidneys and are routinely
shed in human urine. They injected new genetic instructions to reprogramme
cells to become brain cells. But unlike the viral method, those instructions
only stick around temporarily.
Holes are made in the cell membrane
so DNA can enter, but because the DNA doesn’t integrate into the genome, but
just sits in the cyplasm, it exists transiently.
The reprogramming instructions are
therefore eventually lost as the cells divide. With these new genetic
instructions, the cells transformed into brain stem cells, which can turn into
different types of brain cells.
The transformation from kidney cell
to brain stem cell took just 12 days, and within a month, the cells had morphed
into fullfledged brain cells. Unlike other stem cell technologies, the
pee-based brain cells didn’t form tumours when implanted into rats.
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