Monday, February 11, 2013

Scientists develop brain cells from human pee

New York.


Scientists have developed brain cells from Human Pee, which can be useful to treat parkinson & alzheimer.

As a person urinates, skin cells are routinely shed from the lining in the kidney, and it’s these cells that the researchers reprogrammed into stem cells, which can turn into any type of cell in the body, including brain cells.

The Chinese researchers used a newer, safer approach by harvesting skin cells that line the kidneys and are routinely shed in human urine. They injected new genetic instructions to reprogramme cells to become brain cells. But unlike the viral method, those instructions only stick around temporarily.

Holes are made in the cell membrane so DNA can enter, but because the DNA doesn’t integrate into the genome, but just sits in the cyplasm, it exists transiently.

The reprogramming instructions are therefore eventually lost as the cells divide. With these new genetic instructions, the cells transformed into brain stem cells, which can turn into different types of brain cells.

The transformation from kidney cell to brain stem cell took just 12 days, and within a month, the cells had morphed into fullfledged brain cells. Unlike other stem cell technologies, the pee-based brain cells didn’t form tumours when implanted into rats.

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